Selected publications

• Thomas E. Callis, Kumar Pandya, Hee Young Seok, Ru-Hang Tang, Mariko Tatsuguchi, Zhan-Peng Huang, Jian-Fu Chen, Zhongliang Deng, Bronwyn Gunn, Janelle Shumate, Monte S. Willis, Craig H. Selzman, Da-Zhi Wang. 2009. MicroRNA-208a is a regulator of cardiac hypertrophy and conduction in mice. J Clin Invest 119:2772–2786.
• RL. Neppl and DZ Wang, 2009. Smooth(ing) muscle differentiation with microRNAs. Cell Stem Cell 5:130-2.
• Yang L, Jiang J, Drouin LM, Agbandje-McKenna M, Chen C, Qiao C, Pu D, Hu X, Wang DZ, Li J, Xiao X. 2009. A myocardium tropic adeno-associated virus (AAV) evolved by DNA shuffling and in vivo selection. Proc Natl Acad Sci U S A. 106:3946-3951
• Jian-Fu Chen, Elizabeth P. Murchison, Mauricio Rojas, Ruhang Tang, Mariko Tatsuguchi, Thomas E. Callis, Scott M. Hammond, Gerhard Meissner, Craig Selzman, Michael Schneider, Gregory J. Hannon, Cam Patterson and Da-Zhi Wang. 2008. Targeted Deletion of Dicer in the Heart Leads to Dilated Cardiomyopathy and Heart Failure. Proc. Natl. Acad. Sci. U. S. A. 105: 2111-2116
• Tang RH, Zheng XL, Callis TE, Stansfield WE, He J, Baldwin AS, Wang DZ*, Selzman CH*.2008. Myocardin inhibits cellular proliferation by inhibiting NF-kappaB(p65)-dependent cell cycle progression. Proc. Natl. Acad. Sci. U. S. A. 105: 3362-3367 (*Co-corresponding authors).
• Thomas E. Callis and Da-Zhi Wang. 2008. Taking microRNAs to heart. Trends in Molecular Medicine 14: 254-260.
• Chen, J, Thomas, T.E. and Wang, D. 2009. miRNAs in muscle disorder. J. Cell Sci. 122(Pt 1):13-20.
• Xing W, Zhang TC, Cao D, Wang Z, Antos CL, Li S, Wang Y, Olson EN, Wang DZ. 2006. Myocardin Induces Cardiomyocyte Hypertrophy. Circ Res. 98: 1089-1097.
• Chen JF, Mandel EM, Thomson JM, Wu Q, Callis TE, Hammond SM, Conlon FL, Wang DZ. 2006. The role of microRNA-1 and microRNA-133 in skeletal muscle proliferation and differentiation. Nat Genet. 38: 228-233.
• Callis TE, Cao D, Wang DZ. 2005. Bone morphogenetic protein signaling modulates myocardin transactivation of cardiac genes. Circ Res. 97: 992-1000.
• Cao D., Wang, Z., Zhang C., Oh, J., Xing, W., Li, S., Richardson, JA, Wang*, D-Z, and Olson*, EN. 2005. Modulation of smooth muscle gene expression by association of histone acetyltransferases and deacetylases with myocardin. Mol. Cell. Biol. 25, 364-376. (*Co-corresponding authors).
• Wang Z, Wang D.-Z, Hockemeyer D, McAnally J, Nordheim A, Olson EN. 2004. Myocardin and ternary complex factors compete for SRF to control smooth muscle gene expression. Nature. 428, 185-189.
• Wang, D.-Z. and Olson, EN, 2004. Myocardin and cardiac and smooth muscle gene expression. Curr Opin Genet Dev. 14, 558-566.
• Shin, C. H., Liu, Z.-P., Passier, R., Zhang, C.-L., Wang, D.-Z., Harris, T. M., Yamagishi, H., Richardson, J. A., Childs, G., and Olson, E. N., 2002. Modulation of cardiac growth and development by HOP, an unusual homeodomain protein. Cell 110, 725-735.
• Wang, D.-Z., Chang, P.S., Wang, Z, Sutherland, L., Small, E., Krieg, P.A. and Olson, E.N., 2001. Activation of cardiac gene expression by Myocardin, a transcriptional cofactor for serum response factor. Cell 105, 851-862.
• Wang D.-Z., Li, S., Hockemeyer, D., Sutherland, L.B., Wang, Z., Schratt, G., Richardson, J.A., Nordheim, A., and Olson, E.N., 2002. Potentiation of serum response factor activity by a family of myocardin-related transcription factors. Proc. Natl. Acad. Sci. U. S. A. 99, 14855-14860.
• Mariko Tatsuguchi, Hee Young Seok, Thomas E. Callis, J. Michael Thomson, Jian-Fu Chen, Martin Newman, Mauricio Rojas, Scott M. Hammond and Da-Zhi Wang, 2007. Expression of microRNAs is dynamically regulated during cardiomyocyte hypertrophy. J Mol Cell Cardiol. 42: 1137- 1141.
• Xiaochun Long, Esther E. Creemers, Da-Zhi Wang, Eric N. Olson, and Joseph M. Miano 2007. Myocardin is a bifunctional switch for smooth versus skeletal muscle differentiation Proc. Natl. Acad. Sci. U. S. A. 104:16570-16575