Wang Laboratory

Transcriptional and epigenetic control of mammalian cardiovascular development and function

Current studies focus on the identification of cell growth and differentiation signals that modulate the transcriptional activities of myocardin family of transcription factors. We are also investigating how pathophysiological signals, such as cardiac hypertrophy and congenital heart failure, mediate change in myocardin-dependent cardiac gene expression. In addition, we study how epigenetic factors, which modify chromatin, impact cardiac transcription factors and cardiac gene expression during cardiovascular development.

Next to:
miRNAs in cardiac muscle development and function